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Augmentin is an antibiotic. It is adapted to looking for the short-term treatment of a swarm of ordinary infections:
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infections of the respiratory district (airways and lungs) such as tonsillitis, sinusitis, otitis media (infection of the midway appreciation), exacerbation (flare up) of bronchitis and pneumonia;
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infections of the urinary booklet (the structures that maintain urine in the stiff);
infections of the epidermis and cushy tissues (the structures just below the skin);
It can also be hand-me-down as a service to more momentous infections, such as bone or intra-abdominal infections. It can be employed in the preventing of some infections.
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Augmentin, also known as ‘coamoxiclav’, contains two physical substances: amoxicillin, which is an antibiotic relationship to the beta-lactam kith and kin (the same people as penicillins), and clavulanic acid, which is a ‘beta-lactamase inhibitor’. When Augmentin is rapt in the cadaver, the amoxicillin component kills the bacteria that are causing the infection, while the clavulanic acid component blocks an enzyme, betalactamase that franchise the bacteria to ravage amoxicillin. As a result, the antibiotic can work for longer, and is more effective in difficult bacteria. The proportion of amoxicillin to clavulanic acid can vary from 16:1 (one gram of amoxicillin to 62.5 mg clavulanic acid) to 2:1 (250 mg of amoxicillin to 125mg of clavulanic acid).
Augmentin is available as tablets, said suspensions and solutions for injections or infusion (drip into strain). It is also readily obtainable secondary to other trade names, such as Augmentan, Augmentine, Clavamel, Clavamox, Clavepen, Clavulin, Clavumox, Clavurion, Neoduplamox, Noprilam, Pangamox, Penilan and Spektramox.
Why was Augmentin reviewed?
Augmentin is authorised in the EU via native procedures. This has led to divergences across Colleague States in which this medicine is approved, and in the retreat the prescription can be used, as seen in the differences in the Summaries of Output Characteristics (SPCs), labelling and package deal leaflets in the countries where the medicines are marketed.
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On 28 January 2008, the European Commission referred the matter to the CHMP in law to harmonise the marketing authorisations by reason of Augmentin in the EU.
What are the conclusions of the CHMP?
The CHMP, in the light of the figures submitted and the scientific review within the Cabinet, was of the viewpoint that the SPCs, labelling and package leaflets should be harmonised across the EU. The areas harmonised catalogue: