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Augmentin is an antibiotic. It is used for the short-term treatment of a swarm of common infections:
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infections of the respiratory treatise (airways and lungs) such as tonsillitis, sinusitis, otitis media (infection of the mesial appreciation), exacerbation (flare up) of bronchitis and pneumonia;
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infections of the urinary tract (the structures that support urine in the stiff);
infections of the fell and quiet tissues (the structures lately deeper the scrape);
It can also be used for more momentous infections, such as bone or intra-abdominal infections. It can be employed in the mitigating of some infections.
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Augmentin, also known as ‘coamoxiclav’, contains two active substances: amoxicillin, which is an antibiotic affinity to the beta-lactam people (the selfsame blood as penicillins), and clavulanic acid, which is a ‘beta-lactamase inhibitor’. When Augmentin is absorbed in the body, the amoxicillin component kills the bacteria that are causing the infection, while the clavulanic acid component blocks an enzyme, betalactamase that authorize the bacteria to ravage amoxicillin. As a result, the antibiotic can effectuate representing longer, and is more possessions in extermination bacteria. The proportion of amoxicillin to clavulanic acid can modify from 16:1 (inseparable gram of amoxicillin to 62.5 mg clavulanic acid) to 2:1 (250 mg of amoxicillin to 125mg of clavulanic acid).
Augmentin is ready as tablets, oral suspensions and solutions in the course of injections or infusion (drip into hint). It is also at one's disposal secondary to other swap names, such as Augmentan, Augmentine, Clavamel, Clavamox, Clavepen, Clavulin, Clavumox, Clavurion, Neoduplamox, Noprilam, Pangamox, Penilan and Spektramox.
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Why was Augmentin reviewed?
Augmentin is authorised in the EU via nationalistic procedures. This has led to divergences across Colleague States in which this medicine is approved, and in the retreat the medicine can be used, as seen in the differences in the Summaries of Product Characteristics (SPCs), labelling and package leaflets in the countries where the medicines are marketed.
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On 28 January 2008, the European Commission referred the subject to the CHMP in class to harmonise the marketing authorisations on Augmentin in the EU.
What are the conclusions of the CHMP?
The CHMP, in the sparkle of the facts submitted and the painstaking powwow within the Cabinet, was of the point of view that the SPCs, labelling and carton leaflets should be harmonised across the EU. The areas harmonised count: